Its job is to: Signal your pancreas to release insulin Slow down how quickly your stomach empties Tell your brain youre full People with type 2 diabetes often dont produce enough GLP-1, or their bodies dont respond to it properly
Last reviewed: July 12, 2026 Last updated: July 12, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Notably, discontinuation is associated with weight regain and partial or complete reversal of improvements in cardiometabolic risk factors, including inflammatory markers, blood pressure, lipid profile, and blood glucose levels
Postponing GLP-1 RAs before endoscopic intervention or surgery may hinder diabetes management and increase cancellation rates without significant advantages
These therapies, initially designed for type 2 diabetes, have demonstrated significant weight loss benefits, leading to their expanded use in obesity management
JAMA 314 , 687699 (2015)
