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It is also important to note that Mounjaro may reduce the effectiveness of oral contraceptives , particularly during the initial weeks of treatment or after dose increases, due to delayed gastric emptying

303 Moreover, hepatic iron accumulation can induce the transcription expression of ACSL4 by activating the transcription factor c-Myc, and further aggravate the development of MASH through ferroptosis

Beyond blood sugar control, these drugs also slow stomach emptying and reduce appetite, which can lead to weight loss

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