Temperature fluctuations pose a more subtle threat
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Occasional nausea is common with GLP-1 RAs, but persistent vomiting (GLP-1 related or not) can deplete electrolytes significantly.Hyponatremia and hypernatremia (sodium imbalance)Sodium abnormalities typically only occur when significant vomiting, diarrhea, dehydration, or excessive water intake accompany GLP-1 RA use."Sodium can trend low (hyponatremia) if large amounts of free water are consumed without adequate electrolytes, or high (hypernatremia) if fluid intake is inadequate," Dr
Food and Drug Administration and may have quality issues and other problems and risks associated with them
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N Engl J Med 389(12):10691084