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Mechanistically, this was associated with increased BrdU-positive neurons, preservation of dopaminergic neurons (via elevated tyrosine hydroxylase and dopamine transporter levels), enhanced antioxidant defenses (e.g., catalase, GPX1/2, HO-1), and upregulation of autophagy markers such as LC3-II and Beclin-1

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The spray configuration is used in research applications where a pre-packaged intranasal or topical delivery mechanism is preferred over manual reconstitution and syringe preparation

The Figure 3 illustrates the potential activity of phytochemicals in attenuating interstitial cystitis

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