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Therefore, identifying precise and effective therapeutic targets is crucial to prevent the damage and inflammation caused by kidney stones

Since the cellular synthesis of glutathione is ATP-dependent, decreased ETC activity also undermines glutathione synthesis, further exacerbating oxidative stress in a vicious cycle [8]

Amongst these genes, murA , murB , murC , murD , murE , murF , murG , mraY , ddl , encode for 7 essential and 2 redundant proteins leading the synthesis of cytosolic PGN precursors, where MurA, MurB, MurC, MurD and MurE catalyze the very first steps of the process, converting uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) to form UDP-N-acetylmuramic acid pentapeptide [67]

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The percentage increase in bacterial growth at 48 h was determined as mentioned above

H., Nyengaard, J