Those are FDA-approved medications proven to mimic the GLP-1 hormone and are prescribed for obesity or diabetes
Furthermore, cardiomyocyte GLP-1R plays an important role in natriuresis
Furthermore, cardiovascular results for oral semaglutide were similar to the results observed in the SUSTAIN-6 trial with injectable semaglutide, suggesting that the oral and SC formulations share similar cardiovascular safety profiles
Rosenstock J, Frias J, Jastreboff AM, Du Y, Lou J, Gurbuz S, Thomas MK, Hartman ML, Haupt A, Milicevic Z, et al
Proactive management of tirzepatide's gastrointestinal effects can reduce the risk of complications that might lead to rectal bleeding
Some individuals may experience mild digestive sensitivity early on