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When combined with lifestyle changes of dietary modification and a structured exercise program, SG can provide beneficial results for adults with BMI 30, or BMI of at least 27 plus diabetes, hypertension, dyslipidemia, obstructive sleep apnea, vascular disease, or history of myocardial infarction [78]

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After several weeks on the initial dosage, physicians may suggest a gradual increase based on individual response, ensuring that at least one dose is effective

It cannot remove confounding from prescribing patterns, access to care, or simultaneous behavior change