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Why Doctors Prescribe Zoloft and Wellbutrin Together How This Combination Works in Your Brain Common Side Effects of the Combination Serious but Rare Side Effects Important Drug Interactions Starting the Combination Safely Monitoring and Follow-Up Care Cost Considerations and Affordability When This Combination May Not Be Right Alternative Treatment Options Working with Your Healthcare Team Making an Informed Decision References Understanding Zoloft and Wellbutrin Zoloft (sertraline) belongs to a class of medications called selective serotonin reuptake inhibitors or SSRIs

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