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When mitochondrial function declines, tissues that require constant energy supply such as muscles, nerves, and the brain begin to suffer

10.1158/0008-5472.CAN-19-0369 Cancer Res

Inconsistent dosing represents the most frequent mistake - skipping days or irregular timing disrupts the muscle saturation process that underlies creatine's benefits

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It may also help to reduce muscle damage and promote muscle recovery

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