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Why GLP-1 Medications Work for Some Women with Lipedema and Not Others: Genetics, Metabolism & Anti-Inflammatory Nutrition Virtual Event March 12 @ 6:30 pm 7:15 pm Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and newer dual agonists such as tirzepatide are transforming obesity care, yet many women with lipedema experience highly variable resultsfrom dramatic weight loss to almost no change at all