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The core mechanisms of AR cell therapy involve immunomodulation and tolerance induction

As the disease progresses, the cerebral glucose hypometabolism that appears in the preclinical phase of AD gradually worsens, leading to increasingly severe brain energy disorders

Endogenous oxalate synthesis is the result of the non-enzymatic breakdown of ascorbic acid and the oxidation of glyoxylate catalyzed by lactate dehydrogenase (LDH) (Fig