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The naturally occurring peptide GHK-Cu (GHK from glycyl-L-histidyl-L-lysine bound to a copper ion), which affects 31.2% of the human genes by either activating or deactivating them (based on a criterion of a reduction or increment in gene activity of more than 50%), meaning that it works by inducing epigenetic alterations in the cells

1 2 Higley, M.J., Sabatini, B

10.1016/j.neuron.2017.02.005 Neuron 29 FunfschillingU.SupplieL

Triggers, inhibitors, mechanisms, and significance of eryptosis: the suicidal erythrocyte death

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