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Rats were then placed in the Context A operant chamber

The central nucleus of the amygdala plays a crucial role in mediating hypophagia, which is caused by GLP-1 and GLP-1RAs

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Gastrointestinal effects (nausea, diarrhea) are common initially

While cardiovascular outcome data for retatrutide is still accumulating, the prudent approach for anyone with active cardiovascular disease is to remain on compounds with established cardiovascular safety profiles

Prescription GLP-1 medicines can cause side effects including nausea, vomiting, diarrhoea, constipation, and abdominal discomfort