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As no significant differences in serum homocysteine, cystathionine (Figures 4 and 5) or serine levels [60, 69, 70, 75] were observed in children with autistic disorder compared to those without, it can be inferred that the low levels of cysteine may be caused by decreased cystathione lyase activity and/or increased utilisation of sulphate and/or taurine and/or lower dietary intake or absorption of cysteine in children with autistic disorder

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However, in the same studies, females show greater activation of zif268 in the dorsal CA3 compared with males, which is inconsistent with the interpretation of greater activity in the hippocampus accounting for the sex differences in maturation timelines