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Gender in endocrine diseases: Role of sex gonadal hormones

Glutathione deficiency may promote cancer initiation (by failing to protect DNA from oxidative damage), while elevated glutathione in established tumors may promote cancer progression and treatment resistance (by protecting cancer cells from chemotherapy and radiation) [2][5]

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It plays a crucial role in lipid oxidation and energy production by transporting long-chain fatty acids to the mitochondrial matrix, where they are oxidized (burned) to release energy