As shown in Fig.6h, D-CuP exhibited significantly stronger binding affinities, with equilibrium dissociation constants (KD) of 3.8 10 M for p53 and 1.81 10 M for HDAC7
The authors also acknowledge Hui-Ying Wang of the Public Platform of State Key Laboratory of State Key Laboratory of Natural Medicines at China Pharmaceutical University for the use of analytical instrumentation facilities
sodium hyaluronate provides standard surface hydration
Cells were incubated with rabbit polyclonal antibody against CD206 (1:500, Cat No
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In vitro biostability of M-CuP and D-CuP against Proteinase K 1 mM D-CuP and 2 mM M-CuP aqueous solutions (1 mL) were incubated separately with Proteinase K (10 U mL 1 , 100 L) at 37 C for 0, 1, 2 and 4 h