Whats more, they are not recommended for patients with certain health conditions, including a history of medullary thyroid cancer
Among the rare ocular side effects of GLP-1RAs is non-arteritic anterior ischemic optic neuropathy (NAION), which can cause permanent loss of vision, states the report, Glucagon-like Peptide-1 Receptor Agonists and Ocular Health: Guidance for Optometric Practice. The report was first presented at the 2025 Optometry's Meeting | 5th World Congress of Optometry and is meant to provide critical guidance to doctors of optometry treating patients on GLP-1RAs
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Patient feedback so far shows that although most folks dig the accelerated weight loss speed, others experience early side effects, particularly GI ones, which can occasionally decelerate or even halt momentum
Some vials contained something completely different from what the label said (FDA, 2025)
A randomized clinical trial published in JAMA Psychiatry demonstrated reduced alcohol craving and consumption among participants receiving semaglutide, with secondary reductions in cigarette use among smokers (Hendershot et al., 2024)