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Ozempic causes constipation in approximately 515% of patients by slowing gastric emptying as part of its GLP-1 receptor agonist mechanism

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Peer review Peer review information Nature Medicine thanks George Bray, Amanda Adler, Victor Volovici and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Hyperglycaemia also disrupts tubuloglomerular feedback, causing afferent arteriolar vasodilation and exacerbating glomerular hyperfiltration

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