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This understanding moves clinical practice away from a weight-centric paradigm and toward a more biology-centric view of cardiometabolic health

[1] The shuttle is regulated at the CPT-I level, being inhibited by malonyl-CoA from beta oxidation, preventing a futile cycle

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Further investigation revealed that the dosage of the L-glutathione administered to the patients contained excessive bacterial endotoxin, with some results as high as five times the appropriate limit

Single-nucleus RNA-seq libraries were generated using a Chromium Single Cell 3 Library and Gel Bead Kit v3 (10 Genomics, Pleasanton, CA) according to the manufacturers protocol