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Whereas it is unlikely that the topical preparation as such immediately and directly reaches the hair bulb region, it has been shown that drug delivery to the skin occurs also through the hair follicles [32]

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499 Ustekinumab is an effective biologic for the treatment of ulcerative colitis, especially for patients with moderately to severely active ulcerative colitis

This consistency is important for researchers doing long term studies or multi-phase research projects where compound variability can affect experimental outcome