the satiety signal barely fires
Human ACE2 expression is high in tubular epithelia (from kidney), and the viral hijack of this enzyme could alter sodium transport, affect blood volume/pressure and lead to AKI 308
What we prioritize first Before focusing on GLP-1 dosing terminology, we prioritize the clinical fundamentals that have the strongest relevance to cognitive longevity: blood pressure optimization ApoB, LDL, triglyceride, and lipoprotein(a) risk assessment insulin resistance and glucose-pattern evaluation visceral fat and body-composition measurement resistance training and aerobic fitness sleep quality and sleep apnea evaluation when appropriate hearing and vision support nutrition quality and protein adequacy alcohol moderation inflammation and immune-metabolic context hormone evaluation when clinically indicated social connection, cognitive engagement, and meaningful activity None of these interventions is glamorous by itself
Aim for steady, sustainable sessions rather than dramatic swings, and treat promotions as optional accelerators instead of guarantees
doi: 10.1016/j.jand.2022.01.014 50
& Wright, T
