Splitting this into two 1.25mg injections is technically possible but rarely practical
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Besides contributing to PCOS-associated hyperandrogenism, insulin resistance is also linked the development of impaired glucose tolerance and type 2 diabetes mellitus [48], in both obese and non-obese women with PCOS [49]
However, high blood sugar can occur if semaglutide is stopped abruptly in patients also managing diabetes
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It was initially discovered that GLP- 1 activates adenylate cyclase in tissue from the central nervous system (CNS) [53]