Experiments in islet cell models have shown that intracellular signalling after GLP-1R agonist binding occurs via two pathways, one of which (cyclic adenosine monophosphate generation) enhances insulin release, while the other (-arrestin recruitment) causes GLP-1R receptor internalisation, and hence reduces cellular sensitivity to ligand
Bhalla, S., Mehan, S., Khan, A
Hyperandrogenism is associated with earlier age of onset of idiopathic intracranial hypertension in women
Berries: Blueberries, strawberries, and other berries are rich in antioxidants, which can help lower inflammation and improve overall health
*Correspondence: Jens Juul Holst [email protected] This article was submitted to Molecular and Structural Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Pavo, G.J