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Con este tratamiento las lesiones fueron resolvindose progresivamente con descamacin, hasta su desaparicin casi total en una semana, quedando mnima pigmentacin residual

Romeo et al., 2015)

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O 2 - attacks thiols and ascorbate as well as iron sulfur clusters in proteins and thus disrupts the proteins structure and leads to a loss of its function

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Thus, in an experimental model of DOX-induced POI in adult female albino rats, this research seeks to assess the possible consequences of SP and/or L-car on the prevention of primordial follicular reserve depletion, preservation of ovarian follicular structure and function, and improvement of long-term post-chemotherapy fertility utilizing immunohistochemistry, histology, biochemistry, and molecular studies