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doi: 10.1016/j.jpainsymman.2006.09.001 35 HolckAWolkowitzOMellonSReusVNelsonJWestrinet al

Longevity protocol: Dose: 0.5-1mg daily (lower end) Frequency: 3-5 times weekly Cycle: 8 weeks on, 4 weeks off, indefinite repetition Combine with: Overall health optimization (sleep, nutrition, exercise) Lower doses for longevity reduce cost and theoretical concerns about long-term copper peptide use while potentially maintaining meaningful benefits

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10.1165/rcmb.2008-0012OC 164 MirzaeiH.KhoiM.AziziM.GoodarziM

Key aspects of the PESTO trial design include: While PESTO is designed to provide level 1 evidence on the safety and efficacy of perispinal etanercept in chronic stroke patients, the design has been criticized by some experts

ZJJ, KB, HYJ, and YYB analyzed the data and wrote the manuscript