It is not a medical treatment for any condition
Tchernof A, Desprs JP
GLP-1 Drug Shortages and Compounding July 2024 IPD has released a new podcast episode, GLP-1 Drug Shortages and Compounding," where Alyssa Guest, PharmD, discusses the glucagon-like peptide-1 (GLP-1) drugs and how interest in weight loss, viral social media posts, celebrity endorsements, illegitimate compounding, and drug shortages have all impacted access to GLP-1s
In addition, a single dose administration of 3 g/kg of PGN into the stomachs of baboons resulted in 36 mg/kg being excreted in the urine over 24 hour period, again indicating intestinal absorption of PGN, albeit in very small quantities (Beattie et al
Additionally, Melanotan 2 has been associated with systemic pigmentation changes including increased freckle appearance and mole darkening to greater degrees than PT-141
This extra effect led to studies and eventually approvals for weight management purposes