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4.3 The dual role of imbalances in hyaluronic acid metabolism in glycocalyx damage HA has a wide variety of receptors, including cluster of differentiation 44 (CD44), HA-mediated motility receptor, lymphatic endothelial receptor-1, endocytosis-activated HA receptor, and Toll-like receptor 4, and is thus a potent signaling molecule with a range of effects that plays a crucial role in the development of sepsis (68)
Proc Natl Acad Sci USA 91:36803684 Lobo V, Patil A, Phatak A, Chandra N (2010) Free radicals, antioxidants and functional foods: impact on human health
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The practical research difference: 5-Amino-1MQ modulates an entire metabolic regulatory system (NAD+ SIRT1 AMPK), making it useful for studying mitochondrial dysfunction, insulin resistance, and energy balance
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