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Rotate injection sites (abdomen, thighs, upper arms) systematically to reduce local irritation and lipohypertrophy [13]
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Life (Basel) 2022, 12(11)
This has led many to use it for weight management
81,82 Aging also promotes the proinflammatory polarization of monocytes by increasing the plasma saturated fatty acid concentration, thereby increasing the production of IL-6 and TNF- but inhibiting the production of IL-10 and transforming growth factor- (TGF-1)
When it makes sense: If you have a partner, family member, or caregiver who can assist, the upper arm provides a useful third rotation site
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