By blocking NNMT, 5-amino-1MQ promotes an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor essential for cellular metabolism
It is not commonly found in over-the-counter supplements because it is more expensive and often used in clinical settings
De novo NAD+ synthesis enhances mitochondrial function and improves health
Anecdotal reports of users running 6+ months show continued effectiveness without significant issues
Notably, while KPV may be less potent than -MSH, it still exerts considerable anti-inflammatory effects, particularly in mitigating immediate inflammatory responses
Both injections and oral supplements are generally safe, but very high doses of B12 can cause side effects in rare cases, such as mild digestive issues or headaches