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Both contain GLP-1 receptor agonist activity (semaglutide in CagriSema, the GLP-1 component of retatrutide), which would overlap

10 The standard supplement dose is 2 g taken twice daily (4 g total) for at least 3 months

Most incretin mimetics are subcutaneous injections ranging from twice daily to once weekly, though oral semaglutide (Rybelsus) is available as a once-daily tablet alternative for patients who prefer not to inject

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Frequently Asked Questions Does semaglutide always need to be refrigerated