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Fatigue can have many causesincluding poor sleep, stress, thyroid disorders, or iron deficiencythat B12 injections cannot address

Such conditions include autoimmune conditions such as Crohns disease, celiac disease and ulcerative colitis, which all prevent the body from adequately absorbing nutrients from the intestines

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Allergic Reactions: Although rare, some people may experience itching or a rash

Fever that starts after the injection