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Neuroinflammation and immune dysregulation Research increasingly implicates neuroinflammation in fibromyalgia pathophysiology

It has not been approved for any clinical indication in humans

In healthy individuals, CBF is tightly coupled to the metabolic demands of neurons (Claassen et al., 2021), however, it is unclear whether reduced CBF in ADRD is a cause or consequence of cerebral hypometabolism

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