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Previous studies had reported that GSH undergoes auto-oxidation to produce H 2 O 2 (Albro et al., 1986)

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On the day of recording, neuronal cultures were loaded with Cal-590 AM fluorescent calcium indicator dye (Stratech) following manufacturers instructions

*Correspondence: Xiaohan Zhai, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers