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Subcutaneous may offer slightly more consistent plasma levels, but the practical difference is marginal given the compounds short half-life requiring daily dosing either way

The Vegan Society website states: To get the full benefit of a vegan diet, vegans should do one of the following: eat fortified foods two or three times a day to get at least three micrograms (mcg or g) of B12 a day, OR take one B12 supplement daily providing at least 10 micrograms, OR take a weekly B12 supplement providing at least 2000 micrograms

The choice between medications often depends on individual response and side effect profiles

Improving B12 levels has been clinically linked to better cognitive function, stabilized mood, and the reversal of megaloblastic anemia

5-Amino-1MQ is the only relevant choice

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