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Smart Image Examples Embodiment 1 [0057] Synthesis of Compound 5: [0058] Weigh 15.97g of 2-chlorotriphenyl chloride resin (sub=0.939mmol / g), add it to a solid-phase synthesis column, use Fmoc-AEEA-OH (1.5eq), DIPEA (4.5eq), solvent DCM, Reaction for 1.5h to obtain Fmoc-AEEA-resin, after synthesis, use 20% piperidine / DMF to deprotect, time: 5+15min

However, notably, this protective effect could be disrupted by the antagonist of GHSR, [D-lys3]-GHRP-6 (116)

Serious (rare): Severe gastroparesis in patients with existing diabetic gastroparesis

doi:10.1016/j.progsolidstchem.2006.03.001

After removing the magnetic beads, samples were spun down at 20,000 g for 10 min to remove the remaining beads, and the supernatant was transferred to a scintillation vial with 5 mL of Insta-Gel Plus scintillation cocktail (Perkin Elmer #601339)

The main AEs were nausea, diarrhea, and vomiting