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182 In breast cancer, higher cysteine plasma concentrations are found in patients with higher body weight, 182,183 which is a known risk factor for breast cancer, progression and mortality, 184 further linking cysteine, metabolic dysregulation and cancer

Some of these studies examined sex differences, but did not detect any differences in either the number or proportion of acute lesions or in the numbers of T cells or activated macrophages/microglia within male or female WM lesions (4850)

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In addition, insulin administration is known to result in increased GST gene expression through the PI3K/AKT/mTOR pathway and reduced intracellular oxidative stress, while glucagon decreases such gene expression