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Conclusions Few conclusive results are available from clinical trials and from the literature (Fig

10.1016/j.tips.2025.03.008 87 PiaoY.JinJ.ZhouD.QuanH

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Better absorption is generally seen with a carbohydrate-containing meal, since insulin appears to support cellular carnitine uptake

Other fatty acids, which were found to be decreased by L-carnitine administration, were not decreased by the concomitant administration of L-carnitine and EPA

Under copper depletion, CUA-1 localizes to the basement membrane and effluxes copper into the surrounding tissues 17 , but under copper-rich conditions, CUA-1 is redistributed to lysosome-like organelles in the intestine, the intestinal granules, to detoxify copper 17