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Oxidative stress as an important contributor to the pathogenesis of psoriasis

Political Psychology , 44(3), 156-173

In 2021, his team was the first to demonstrate that SLC25A39 is the transporter that brings glutathione into the mitochondria

DIM (diindolylmethane) DIM is used to stimulate 2 hydroxylation (neutral estrogen pathway) via CYP1A1 and reduce expression of 16 hydroxylation (potential harmful estrogen pathway) through inhibiting CYP3a4

Together, these data demonstrate that ablation of GSH synthesis in mice results not only in reduced expression of lipogenic enzymes but also lower levels of their corresponding lipid species