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Blocking metallothionein-2 expression by copper-doped carbon dots induces cellular antioxidant system collapse for antitumor therapy

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Lancet 381(9863):295302 Bruix J et al (2017) Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial