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However, the therapeutic effect of SSB2 on depression is blocked when GPX4 is knocked out, indicating that SSB2 acts through a GPX4-dependent manner in mediating TLR4/NF-B pathway, exerting its anti-ferroptosis and anti-neuroinflammatory roles (WANG et al., 2023b)

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In contrast to ALMT1-mediated GABA transport, the presence of Al 3+ blocks the influx of GABA from the apoplast to the cytoplasm during ALMT1 transport, while it does not affect the GABA transport facilitated by GAT1 (Long et al

Simmons WK, Burrows K, Avery JA, Kerr KL, Taylor A, Bodurka J, et al