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IBD alters the bone microenvironment by suppressing osteoblasts and activating osteoclasts, leading to reduced bone density and impaired microstructure
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In an announcement of the study on the Vanderbilt website, lead author Khrysta Baig described this as a purely hypothetical scenario, but one that underscores that at current prices, these medications cannot be the only way or even the main way we address obesity as a society. In a more conservative estimate, Bhaig and coauthors consider a case where only about 10% of those eligible for obesity treatment opted for semaglutide, which would result in $27 billion in new costs
However, Wrights experience with the medication soon took a turn for the worse
After treatment with semaglutide, the body weight decreased in a dose-dependent manner
