Furthermore, increased expression of heme oxygenase-1 (HO-1) in microglia and loss of copper chaperone protein (CP) activity in astrocytes contribute to iron deposition in the central nervous system (CNS) and neuronal death [182]
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When not looking at complete adherence to treatment plans, the researchers reported similar results
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In irradiated 3T3 fibroblasts, GHK treatment decreased the expression of p21, a key marker of cellular senescence (Figure 2A)