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Carnitine translocase and transferase components Carnitine/AcylCarnitine translocase Mitochondria import acylcarnitines through carnitine/acylcarnitine translocase (CACT) located in the inner mitochondrial membrane, which catalyzes a mole-to-mole exchange of carnitines/acetylcarnitines and acylcarnitines 56

Across the 52 weeks of ATTAIN-MAINTAIN, participants treated with orforglipron gained an average of 5 kg (11 lbs) in the tirzpatide group and an average of 1 kg (2.2 lbs) in the semaglutide group

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