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Extended sonication should be avoided as it may degrade the peptide

In a 24-week human study (ages 6595), aerobic training reduced oxidative stress markers (MDA, 8-OHdG) and inflammatory cytokines, while increasing total antioxidant capacity

All authors approved the final version of this manuscript and agree to be accountable for all aspects of the work

Pharmaceutics, 15(10), 2490

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Iron has been found to upregulate SLC7A11mRNA as a protective mechanism via increasing activities of the ROS-nuclear factor erythroid 2-related factor 2 (NRF2) signaling, which helps to inhibit ferroptosis in BMDM (79)