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Value-based healthcare models increasingly recognize the importance of clinical outcomes rather than simply drug acquisition costs

A novel gastric pentadecapeptide bpc 157 with different beneficial activities and anticonvulsant effect interacting with gabaergic system could improve diazepam efficacy coadministered (10 microg/kg, 10 ng/kg i.p.) with diazepam (5.0 mg/kg i.p.) twice daily for 10 days, since diazepam chronic medication would otherwise predispose for diazepam- tolerance/withdrawal development (shorter latency to convulsion after convulsant)

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609 Edaravone inhibits ferroptosis through the SIRT1/Nrf2 signaling pathway and has therapeutic potential for depression, TBI and stroke

Furthermore, tau aggregation can impair mitochondrial dynamics, leading to decreased mitochondrial motility and compromised mitochondrial function

Heliyon 9 (6), e17488