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Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2(+ve) breast cancer metastasis

M., Hinkov, H., Hu, C

doi: 10.1111/ejn.15502 6 LiXSongDLengSX

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Another glutaminase inhibitor, JHU-083, extensively inhibits Gln-metabolizing enzymes and increases the concentrations of Gln and glucose in the TME by inhibiting glycolysis, relieving the hypoxic state