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Recently, the exercise-induced microRNA miR-129-3p has been proposed as a promising candidate for exercise mimetics, as it maintains muscle integrity via the PARP1SIRT1PGC1 axis and ameliorates muscle atrophy and mitochondrial dysfunction.[86] Electrical pulse stimulation (EPS) has been used to mimic muscle contraction in myotubes and induce transcriptional changes comparable to in vivo exercise

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2017 May 15;8(3):511-519

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