Sudden appetite changes can also indicate thyroid dysfunction, uncontrolled diabetes, or other endocrine disorders that require investigation
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Side effects tend to mirror those of GLP-1 agonists: Nausea Diarrhea Decreased appetite Possible gallbladder effects (as with all rapid weight loss) Minimal risk of hypoglycemia when used without insulin Importantly, GIP on its own does not cause hypoglycemia , making it a relatively safe therapeutic target
Importantly, these studies demonstrate a consistent pattern: whilst retained gastric contents are significantly more common in GLP-1 RA users, the absolute rates vary considerably depending on patient factors, medication duration, and assessment methods [35]
It is expressly not a GHRH analogue