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If melanonychia has atypical features (currently we still primarily consider atypical features to be the ABCDEFs), then a tangential shave biopsy of the matrix is warranted to exclude melanoma

Enterocutaneous fistulas: a primer for radiologists with emphasis on CT and MRI

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These symptoms are typically mild to moderate in severity and tend to diminish over time as the body adjusts to the medication, particularly when dose escalation follows the recommended gradual schedule

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