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BMJ Nutrition, Prevention & Health

Whilst an accidental double dose is not typically life-threatening, it significantly increases the risk of adverse effects, particularly gastrointestinal symptoms and low blood sugar

Biochem Pharmacol (2013), Aron, L., Ngian, Z.K., Qiu, C

KLF4, Kruppel-like factor 4

doi: 10.1111/j.2040-1124.2010.00022.x

CNS actions GLP-1R signaling plays a critical role in the maintenance of glucose homeostasis as deletion of the GLP-1R in mice results in impaired glucose tolerance (Scrocchi et al., 1996) and physiological levels of GLP-1 enhance meal-related insulin secretion in humans (Kreymann et al., 1987